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UNDERSTAND

What is depression?

A first overview of a condition, its possible effects and its different patterns over time.

Source comparison · 29 October 2026

At a glance

Depression affects more than mood. Individual signs alone cannot establish a diagnosis.

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SourcesReading & printing

General information for adults. Not medical or psychotherapeutic advice; not a substitute for examination, diagnosis or treatment.

More than a sad day

Depression is a mental health condition. Persistently low mood or a loss of pleasure and interest are central features. It differs from ordinary changes in mood. [2]

What can it feel like?

Energy, concentration, sleep and everyday life can also be affected. Some people describe emotional emptiness; others struggle with familiar tasks. Experiences differ from person to person. [1]

Why is there no simple explanation?

Biological, psychological and social influences can interact. A stressful event may play a role, but depression can also occur without an obvious trigger. General patterns do not automatically explain an individual person’s experience. [1][2]

What is a depressive episode?

The term describes a period of depressive symptoms. Some people experience one episode; symptoms can also return or persist. A general description cannot predict an individual person’s course. [1]

What can this overview tell you?

It explains terms, but cannot tell whether you or someone else has depression. Diagnosis considers symptoms, duration and their impact together. [3] For personal health questions, consult an appropriately qualified professional.

READ FURTHER & CHECK THE SOURCES

Sources and context

How should I interpret these sources?

Source notes identify the provider, their use in this article and known limitations. The source-comparison date below is not the original publication date. No update date is assumed where none is available. General findings cannot automatically be applied to an individual; independent medical review of this draft is pending.

  1. IQWiG · InformedHealth.org: Depression ↗

    Provider / domain: www.informedhealth.org

    Plain-language overview. Used for terminology, symptoms and course.

  2. WHO: Depressive disorder (depression) ↗

    Provider / domain: www.who.int

    International overview. Used for the distinction from mood changes and contributing factors.

  3. German National Clinical Practice Guideline · Chapter 2 ↗

    Provider / domain: www.leitlinien.de

    German-language clinical guideline. Used for diagnostic assessment and the limitations of questionnaires.

Research and source comparison: 29 October 2026. Prepared with AI assistance. Editorial responsibility: Mario V.W.B.R. Obst. Independent medical expert review is pending. Independent medical expert review has not taken place.

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depression.zone

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depression.zone offers general information about depression. Its content does not replace medical or psychotherapeutic advice, examination or treatment.

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