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Signs & assessment

What symptoms can occur – and why does diagnosis require more than a list?

Source comparison · 29 October 2026

At a glance

Signs are clues. Professional assessment also considers other possible explanations.

Read sources & limitations ↓
SourcesReading & printing

General information for adults. Not medical or psychotherapeutic advice; not a substitute for examination, diagnosis or treatment.

What changes might be noticeable?

Examples include persistent low mood, reduced enjoyment, low energy and problems with sleep or concentration. These examples are not a complete checklist and cannot be used for self-diagnosis. [1]

Why ask about duration and daily life?

Professionals consider how long symptoms have lasted and how much they affect a person’s life. The often-mentioned duration of at least two weeks is one diagnostic consideration; it does not establish depression by itself. [2]

What does assessment involve?

A conversation explores symptoms, their course, health history and life circumstances. Physical examinations or laboratory tests may help investigate other explanations, such as a thyroid condition. A blood test alone does not diagnose depression. [2][3]

What can questionnaires do?

They can identify possible signs and record symptoms in a structured way. An elevated score does not replace a full diagnostic assessment through direct conversation. [2]

Do you have to wait two weeks?

The diagnostic timeframe is not a requirement to wait. Earlier contact with a professional is appropriate when distress is substantial or there are safety concerns. [3] depression.zone does not assess personal symptoms or replace professional advice.

READ FURTHER & CHECK THE SOURCES

Sources and context

How should I interpret these sources?

Source notes identify the provider, their use in this article and known limitations. The source-comparison date below is not the original publication date. No update date is assumed where none is available. General findings cannot automatically be applied to an individual; independent medical review of this draft is pending.

  1. IQWiG · InformedHealth.org: Depression ↗

    Provider / domain: www.informedhealth.org

    Plain-language overview. Used for terminology, symptoms and course.

  2. German National Clinical Practice Guideline · Chapter 2 ↗

    Provider / domain: www.leitlinien.de

    German-language clinical guideline. Used for diagnostic assessment and the limitations of questionnaires.

  3. NHS: Diagnosis – Depression in adults ↗

    Provider / domain: www.nhs.uk

    Patient information on assessment. Provider’s last review: 5 July 2023; planned review date of 5 July 2026 has passed. Used as a supplementary source only.

Research and source comparison: 29 October 2026. Prepared with AI assistance. Editorial responsibility: Mario V.W.B.R. Obst. Independent medical expert review is pending. Independent medical expert review has not taken place.

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