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UNDERSTAND

Episodes, relapse and persistent depression

Terms for different patterns over time, without turning them into a personal prognosis.

Source comparison · 29 October 2026

At a glance

A condition can follow different patterns. A label describes a course, not a certain future.

Read sources & limitations ↓
SourcesReading & printing

General information for adults. Not medical or psychotherapeutic advice; not a substitute for examination, diagnosis or treatment.

What is an episode?

A depressive episode is a period of depressive symptoms. Some people experience one episode; others experience further episodes. [1]

What is remission?

Remission describes symptoms largely or completely subsiding. It is not a guarantee that symptoms will never return. [2]

What do relapse and recurrence mean?

Both concern symptoms returning. Guidelines may distinguish an early relapse from a later new episode. Read the definition and timeframe used by the source. [2][3]

What does persistent or chronic mean?

Some people experience depressive symptoms for a prolonged period. The source describes different patterns. Duration and severity are separate features that need to be considered together. [1]

Why discuss continuing treatment?

After symptoms improve, clinicians may discuss continuing care to support stability or prevent relapse. This article does not specify a personal treatment duration or a stopping plan. [3]

READ FURTHER & CHECK THE SOURCES

Sources and context

How should I interpret these sources?

Source notes identify the provider, their use in this article and known limitations. The source-comparison date below is not the original publication date. No update date is assumed where none is available. General findings cannot automatically be applied to an individual; independent medical review of this draft is pending.

  1. IQWiG: Forms of depression (German-language source) ↗

    Provider / domain: www.gesundheitsinformation.de

    Patient information on different patterns; not an individual prognosis. Accessed: 29 October 2026.

  2. German National Clinical Practice Guideline · Chapter 3: Treatment planning ↗

    Provider / domain: www.leitlinien.de

    German-language clinical guideline. Used for shared decisions, treatment goals and involving family members.

  3. German guideline: Continuation and recurrence prevention (German-language source) ↗

    Provider / domain: www.leitlinien.de

    Clinical guideline on continuing treatment; individual plans require professional assessment. Accessed: 29 October 2026.

Research and source comparison: 29 October 2026. Prepared with AI assistance. Editorial responsibility: Mario V.W.B.R. Obst. Independent medical expert review is pending. Independent medical expert review has not taken place.

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